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Rating the perfect glucosamine dietary supplements of 2022

Glucosamine performs an necessary function in preserving joint well being. Glucosamine reduces joint irritation and ache from arthritis, and should assist rebuild broken cartilage and gradual the progressive lack of joint house that happens within the illness.

Many individuals discover that glucosamine is useful for different kinds of joint ache as nicely, comparable to sports activities accidents.

Want a glucosamine complement to alleviate your joint ache? Don’t fear, our analysis workforce has you lined.

Listed below are the perfect glucosamine dietary supplements obtainable proper now.

Why You Ought to Belief Us

    Our advisory panel and our analysis workforce rank the perfect well being merchandise and dietary supplements primarily based on efficiency, label accuracy, and the efficacy of the elements within the merchandise.


Final up to date: September 2, 2022
Glucosamine dietary supplements thought-about: 25
Hours of analysis: 37
Specialists reviewed: 8
Scientific papers referenced: 12


Finest Total

1. Reside Acutely aware MoveWell Glucosamine

  • Is a straightforward decide for joint ache
  • Fights irritation, cut back ache, and encourage therapeutic in connective tissue
  • Promotes mobility and adaptability by serving to direct collagen to the joints
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Finest with hyaluronic acid

2. Important Components Glucosamine Chondroitin

  • Helps to cut back joint irritation and enhance the formation of recent cartilage
  • Comes with elements that fight soreness and discomfort to advertise higher mobility
  • Improves long run well being for joints
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Finest with MSM

3. Kirkland Signature Glucosamine With MSM

  • Offers easy and environment friendly dietary supplements that handle your primary wants
  • 750 mg of glucosamine in every pill
  • Has a robust anti-inflammatory impact
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  • Delivers 1000 mg of glucosamine hydrochloride per pill
  • Helps and promote joint well being
  • Accommodates hyaluronic acid that help cartilage regeneration properties of glucosamine
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Finest for irritation

5. Phytochoice Glucosamine Chondroitin

  • It delivers a stability of assorted elements to assist with joint ache
  • Every pill comprises solely 500 mg of glucosamine
  • Strengthens cartilage
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6. Made in Utah Glucosamine Chondroitin Turmeric MSM

  • A barely larger high quality complement with this joint help product
  • 500 mg of glucosamine per pill
  • Has an anti-inflammatory and ache relieving energy within the complement
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7. Zenwise Superior Power Joint Help

  • Finest on the subject of all-around joint regeneration
  • Promotes higher joint mobility for many who have an energetic life-style
  • Advance components that promote energy and adaptability for the joints
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8. USA Nutra Most Power Glucosamine Chondroitin Turmeric MSM

  • Multi-ingredient complement targeted on joint well being
  • 500 mg of glucosamine per pill
  • Helps Irritation
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9. Physician’s Finest Glucosamine Chondroitin MSM

  • Delivers 1500 mg of glucosamine
  • Helps and helps joints and maintains wholesome pores and skin, nails, and hair
  • Gluten free, Soy free, and Non-GMO
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10. Vitabreeze Glucosamine Chondroitin MSM & Turmeric

  • Multi-ingredient joint help complement
  • Vegetarian Complement that’s Non-GMO, gluten free and soy free
  • Very straightforward to swallow capsules
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11. BlueBonnet Glucosamine Chondroitin Plus MSM

  • Has high-quality and high-purity dietary supplements
  • Low glucosamine content material per pill
  • Soy-free, gluten-free and dairy-free
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1. Reside Acutely aware MoveWell Glucosamine

Test the bottom value

MoveWell helps and protects your joints by sustaining cartilage, lubricating joints, and enhance glutathione manufacturing to combat irritation.

It accomplishes this by way of a number of clinically backed elements, together with 600mg of chondroitin, 600mg of MSM, 1500mg of glucosamine, 100mg of AprèsFlex® Boswellia, 100mg of curcumin and 100mg of hyaluronic acid per serving.

MoveWell is freed from inflammatory brokers, together with gluten, soy, dairy, and sugar. It is usually manufactured in a GMP-certified facility within the USA.

For the best possible joint help components, MoveWell glucosamine is the perfect on the market.

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2. Important Components Glucosamine Chondroitin

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Important Components Glucosamine Chondroitin helps to cut back joint irritation and enhance the formation of recent cartilage.

It combines hyaluronic acid, curcumin and MSM with glucosamine and chondroitin to supply a few of the finest joint aid available on the market.

Made within the USA and third get together examined, it’s a superb choice.

3. Kirkland Signature Glucosamine

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Kirkland Signature gives a stable dosage of glucosamine per pill, and consists of MSM as nicely, one other well-liked joint complement that fights irritation and ache.

The capsules have a bit extra binders and fillers than you’ll discover in our prime picks, however the dosage nonetheless makes it a stable decide.

4. Made in Utah Glucosamine

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Made in Utah has a stable 500 mg of glucosamine per pill, together with chondroitin, turmeric, and MSM plus just a few much less widespread extras. Boswellia extract, quercetin, and methionine all add to its pain-relieving energy.

5. Schiff Glucosamine

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Schiff’s glucosamine formulation delivers 1000 mg of glucosamine hydrochloride per pill, together with 1.6 mg of hyaluronic acid, which assists with cartilage regeneration.

The excessive dose is nice, however purists received’t just like the components, emulsifiers, and coloring brokers included within the capsule.

6. Zenwise Joint Help

Test the bottom value

Zenwise is among the many finest on the subject of all-around joint regeneration. Its glucosamine content material (500 mg) is center of the highway, however you’ll additionally discover the natural extracts like boswellia and curcumin, which may be powerful to seek out within the competitors.

7. Phytochoice Glucosamine Chondroitin

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Phytochoice delivers a stability of glucosamine, chondroitin, quercetin, turmeric, and boswellia extract, so it’s a fairly versatile choice. Nevertheless, the uncooked dosage of glucosamine is just not pretty much as good, which hurts its place within the rankings a bit. 

8. USA Nutra Most Power Glucosamine

Test the bottom value

USA Nutra’s tackle glucosamine is fairly good, with 500 mg of glucosamine per pill, in addition to the namesake extras and quercetin and methionine for good measure.

The shortage of additional filler compound is interesting to individuals who wish to preserve the components of their complement to a minimal.

9. Physician’s Finest Glucosamine Chondroitin MSM

Test the bottom value

Physician’s Finest makes a glucosamine complement full of glucosamine, chondroitin, and a specialised type of MSM. The one draw back? The per-capsule dosage is just not so scorching, touchdown it additional down within the rankings.

10. BlueBonnet Glucosamine Chondroitin

Test the bottom value

BlueBonnet delivers a easy, efficient glucosamine complement whose solely weak spot is a fairly low dose per capsule. The complement design is nice, nevertheless it simply doesn’t match as much as the competitors on the subject of dosage.

Class winners

Finest glucosamine total: Reside Acutely aware MoveWell Glucosamine

MoveWell consists of glucosamine alongside an astounding 5 different biologically energetic compounds to combat irritation, cut back ache, and encourage therapeutic in connective tissue. Because of this breadth of elements, it’s our prime suggestion.

Finest glucosamine for irritation: Important Components Glucosamine Chondroitin

Important Components consists of a number of all-natural elements to help with glucosamine’s anti-inflammatory properties. These embody chondroitin, hyaluronic acid,  and boswellia extract—all of that are nice for chopping again on irritation in your physique.

Finest glucosamine for joint ache: Reside Acutely aware MoveWell Glucosamine

With joint-nourishing compounds like hyaluronic acid and chondroitin, plus boswellia and curcumin to chop down on irritation, MoveWell is a straightforward decide for joint ache. 

Finest glucosamine with MSM: Kirkland Signature Glucosamine MSM

If you wish to mix the cartilage-soothing results of glucosamine with the highly effective anti-inflammatory results of MSM, Kirkland is the way in which to go. With 750 mg of every, it’s our prime decide for MSM/glucosamine combos. 

Finest glucosamine for knees: Reside Acutely aware MoveWell Glucosamine

The knee is without doubt one of the most typical areas of arthritis and damage, as a result of excessive forces it must bear throughout strolling and different actions. MoveWell is a good selection for folks with knee ache, as a result of it comprises compounds that fight irritation that happens in response to broken tissue within the knees, and it consists of compounds that encourage therapeutic of connective tissue as nicely. 

Finest glucosamine with hyaluronic acid: Reside Acutely aware MoveWell Glucosamine

Reside Acutely aware delivers glucosamine alongside 100 mg of hyaluronic acid, which is famend for its means to lubricate joint surfaces. The targeted formulation of this complement makes it nice for individuals who wish to benefit from hyaluronic acid’s mobility-enhancing properties. 

Who should purchase glucosamine?

Glucosamine is without doubt one of the hottest and simplest joint dietary supplements for decreasing irritation, treating joint ache, and slowing down or doubtlessly even reversing injury to cartilage. It’s a terrific complement for:

Folks with painful knees, hips, or different joints. Glucosamine can’t work miracles, however many individuals discover that it considerably reduces joint ache, and scientific analysis backs up its potential to decelerate goal markers of joint injury.

Folks with osteoarthritis. A lot of the analysis supporting the usage of glucosamine focuses on osteoarthritis, which causes injury, degeneration, and irritation, suggesting this can be a nice use-case for glucosamine.  

Folks with sports activities accidents to their joints. Glucosamine can do extra than simply assist arthritis: some analysis signifies it’s a helpful strategy to cut back ache from sports activities accidents, like previous knee or ankle sprains that by no means totally healed.

How we ranked

Since glucosamine is so well-studied within the scientific literature, we used the perfect scientific analysis to information our collection of glucosamine dietary supplements, primarily based on the next standards: 

Efficient dosageWe seemed for dosages and formulations that lined up nicely with scientific research —that meant dietary supplements that make it straightforward to take what seems to be the optimum dosage for glucosamine, which is at the least 1500 mg of glucosamine per day.

A concentrate on delivering pure glucosamine. Not like our rankings of general-purpose joint dietary supplements, we put much less emphasis on the inclusion of different doubtlessly biologically energetic compounds like MSM or hyaluronic acid when evaluating the standard of a glucosamine complement.

Whereas extra elements had been a small perk that boosted the scores of some glucosamine dietary supplements in our rankings, our major focus was dosage and purity.

No binders, fillers, or synthetic components. We dropped dietary supplements from consideration in the event that they contained an excessive amount of in the way in which of binders and fillers.

Since glucosamine is already derived from animal merchandise (shellfish, often), it didn’t matter to our analysis workforce whether or not the complement was delivered in a cellulose or gelatin capsule.

The highest performers had been merchandise that successfully delivered a excessive dose of glucosamine whereas protecting further elements to a minimal.

In case you are on the lookout for a glucosamine complement that gives the identical advantages seen in probably the most profitable scientific analysis, you’ll discover it in our rankings.


Glucosamine helps cut back irritation and joint ache. It fights ache by by encouraging cartilage to soak up extra water, protecting the cartilage hydrated (1,2).

Glucosamine may additionally enhance the synthesis of cartilage tissue. Analysis on older adults with arthritis signifies that glucosamine can gradual or halt the development of joint injury in arthritis (3,4).

Glucosamine upregulates synthesis of the constructing blocks of cartilage. Based on a research printed by researchers in Italy, glucosamine sulfate will increase the synthesis of a kind of protein known as proteoglycan, which make up a big quantity of the mass in cartilage (5).

Glucosamine may assist cut back ache from previous sports activities accidents. A research on folks with injury-related, non-arthritic knee ache skilled vital enhancements in ache after taking 2000 mg of glucosamine for twelve weeks (6).

Glucosamine works higher for joint ache than again ache. In distinction to the above outcomes on knee and hip ache, analysis from Norway suggests glucosamine is just not as useful when you’ve got persistent low again ache (7).

Unwanted side effects

Analysis exhibits glucosamine is protected and well-tolerated by nearly everybody. Medical trials haven’t discovered any vital distinction within the charge of unintended effects in glucosamine versus placebo.

Glucosamine is derived from shellfish, so it may set off shellfish allergic reactions. The one potential opposed impact to concentrate on is the truth that glucosamine is derived from marine shells, so anybody with a extreme shellfish allergy ought to keep away from glucosamine dietary supplements.

Advisable dosage

Finest outcomes come from round 1500 mg per day. That quantity comes from a research that examined doses from 750 to 3000 mg per day (8).

Above 1500 mg per day your physique can’t take in any extra glucosamine. Greater doses are nonetheless protected, however don’t present any extra advantages by way of bioavailability.


Q: Why would you are taking glucosamine?

A: Glucosamine is hottest as a complement for joint ache that’s linked to osteoarthritis, and that is the appliance that’s most well-supported by scientific analysis.

Nevertheless, it’s additionally logical to take glucosamine for different joint ache, like knee ache from an acute sports activities damage, or ache and irritation from previous joint accidents that by no means totally went away.

Q: Is glucosamine good on your joints?

A: Glucosamine has been studied closely as a method to enhance joint well being and gradual and even doubtlessly reverse the degenerative progress of osteoarthritis, the place cartilage is progressively broken and infected over time, resulting in ache and incapacity.

Whereas glucosamine can’t work miracles, it does reduce down on a few of the ache and limitations to your regular day by day routine that may be brought on by joint injury and illness.

Q: Do any joint dietary supplements actually work?

A: The most effective scientific analysis helps small however vital advantages from joint dietary supplements primarily based on glucosamine, chondroitin, and MSM as nicely.

Quercetin is one other complement for joint well being that has some analysis supporting it, as does fish oil.

In each of those instances, these joint complement elements are thought to exert antioxidant and anti inflammatory results, chopping down on the cellular-level aggravation within the joint.

Q: Is glucosamine in meals?

A: Glucosamine is just not present in any meals in any vital quantity.

It’s a naturally-occurring compound, however you couldn’t get a dose anyplace close to what’s utilized in scientific supplementation research even in a really nutritious diet.

The one strategy to get glucosamine in any vital quantity is to make use of a glucosamine complement.

Q: Is there anybody who mustn’t take glucosamine?

A: Since glucosamine is derived from shellfish, you shouldn’t take glucosamine if you understand you’ve got a shellfish allergy.

Q: Is glucosamine helpful alongside MSM?

A: Glucosamine is assumed to reinforce the organic efficacy of methylsulfonylmethane, or MSM, which is one other widespread complement used for joint ache.

You’ll usually discover each glucosamine and MSM used as elements in joint dietary supplements, and a few analysis has efficiently examined the efficacy of each together (9,10).

Q: What’s glucosamine chondroitin?

A: Glucosamine chondroitin is a time period utilized to joint dietary supplements that embody each glucosamine and chondroitin, which is a chemically distinct molecule.

Chondroitin is a direct structural part of cartilage, and is assumed to assist increase the synthesis of recent cartilage in broken joints.

Glucosamine additionally helps help joint well being, and most multi-ingredient joint dietary supplements financial institution on each glucosamine and chondroitin being simpler together than alone.

Q: How does glucosamine work?

A: Glucosamine is a precursor to a kind of compound known as glycosaminoglycan, which in flip is used each as a constructing block for cartilage, and as a lubricant and shock absorber inside joints.

Analysis on cartilage tissue means that glucosamine will increase cartilage water content material and will increase cartilage protein synthesis, plus boosts the provide of lubricating and shock-absorbing fluids within the joint house.

Q: How lengthy does it take for glucosamine to work?

A: Most analysis on the usage of glucosamine is at the least just a few months in size, so it is best to strive glucosamine for at the least this lengthy to see if it really works.

One research on utilizing glucosamine to deal with long-term knee ache explicitly examined the time-course of glucosamine’s results and located that many of the advantages attributable to glucosamine had appeared after eight weeks of use (11).

So, when you’ve solely been utilizing glucosamine for a few weeks, chances are you’ll not have been utilizing it lengthy sufficient to get the complete impact of the complement.

Q: What’s the finest time to take glucosamine?

A: The timing of once you take glucosamine is just not significantly necessary, as a result of it’s pretty long-lasting in your physique.

Nevertheless, you do wish to take it each single day at roughly the identical time to get optimum results.

That’s what the pharmacological analysis helps, and is the protocol utilized by probably the most profitable analysis research on utilizing glucosamine.

Q: How lengthy does glucosamine keep in your system?

A: Scientific analysis has estimated the elimination half-life of glucosamine at about 15 hours, which means that after taking a full dose of glucosamine, half of it has been eradicated out of your physique 15 hours later (12).

Because of this after you cease taking glucosamine, it’s going to take just a few days for it to get completely eradicated out of your system.

Because of this comparatively lengthy elimination half life, you don’t should take glucosamine any extra usually than as soon as each day.

Q: What’s glucosamine constituted of?

A: Glucosamine is often made by taking shells from shellfish (like clams or oysters) and breaking down the molecules that make up their shells.

It’s a straightforward, cheap, and efficient strategy to purchase a considerable amount of glucosamine.

This course of can be why it’s endorsed to take glucosamine when you have a shellfish allergy—it’s probably that the allergens current in shellfish are additionally current in glucosamine in hint quantities.

Associated articles


Glucosamine is a complement whose efficacy has been examined by a number of giant scientific trials and has vital advantages on joint ache.

Glucosamine seems to be simplest at stopping the lack of cartilage in your joints that comes from osteoarthritis, and in addition appears to be efficient in lots of (however not all) research analyzing ache and day-to-day operate.

This means that glucosamine is finest used early on to decelerate the development of arthritis, when your ache continues to be delicate.

Glucosamine may be very well-tolerated, which means that you simply don’t want to fret about unintended effects, and the optimum dosage for finest outcomes seems to be round 1500 mg per day.

For BodyNutrition’s #1 glucosamine suggestion, click on right here.

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